The Best Mood Enhancement Supplements: Top 15 Supplements To Improve Mood

Published on February 4th, 2023

Last updated on March 7th, 2023

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Are you feeling down and out? You’re not alone—poor mental health has become increasingly common. So, are you looking for a boost to your mood? Don’t look any further! We have compiled the top 15 mood enhancement supplements that will make you feel as good as new.

Uplifting your mood can be hard work. Taking supplements to help support better mental health can make it easier. One effective solution is using natural best mood supplements. They can help to promote better emotional well-being.

Some amazing mood-enhancing supplements can help keep our minds and bodies in balance:

  • B vitamins;
  • omega-3 fatty acids;
  • zinc;
  • magnesium;
  • and herbal extracts like ashwagandha and St John’s.

Choosing the right supplement can put you in a much brighter mood! So, read on – it’s time to start supplementing your life in the happiest way possible!

1. B Vitamins

This best mood enhancer plays an essential role in the body’s production of serotonin and dopamine. These two hormones are responsible for regulating our emotions and keeping us positive.

Studies have shown that B-complex vitamins, including vitamin B6, reduce symptoms of depression. Additionally, evidence suggests that combining folic acid and vitamin B12 can decrease:

  • homocysteine levels;
  • an amino acid linked to the onset of depression and anxiety. 

Studies have also revealed that the best mood enhancers with vitamins B3 and B6 can improve:

  • cognitive performance;
  • and mental health. 

People with lower levels of Vitamin B are more likely to suffer from depressive symptoms. So if you’re looking for a way to boost your mood and get back to feeling positive, Vitamin B is an excellent choice!

2. Vitamin D

This mood enhancement supplement increases:

  • focus;
  • memory retention;
  • and cognitive functioning.

By supplementing with Vitamin D, you can give your body the necessary nutrients to produce hormones and neurotransmitters that help regulate your mood. This helps to create a natural sense of balance in your brain chemistry.

It allows you to remain emotionally stable even during stress or difficulty. Furthermore, Vitamin D boosts bone and muscle health and reduces fatigue.

3. Omega-3 Fatty Acids

This best mood supplement is a natural way to enhance your well-being. These essential fats are contained in the following:

  • fish;
  • nuts;
  • and some plant oils.

They play an important role in brain health. Studies suggest that Omega-3s can help reduce:

  • symptoms of depression;
  • help you stay focused

Omega-3 fatty acids are beneficial for heart health as well. Research shows that this boost enhancement supplement can:

  • lower triglycerides;
  • reduce arterial inflammation;
  • and decrease the risk of stroke and heart attack.

The American Heart Association advises eating at least two servings of fatty fish a week. It ensures you get your daily dose of Omega-3s.

4. St. John’s Wort

It is a common mood enhancement supplement that has been used for centuries. The main active component of John’s Wort is Hypericin. It helps regulate:

  • serotonin production in the brain;
  • and prevent depression.

This best mood supplement is very safe for most people. It has little to no side effects when taken correctly. This natural supplement is gentle on the body yet powerful enough to make a difference in how one feels.

5. Valerian

Valerian is an ancient natural supplement. It contains the active ingredients:

  • valerenic acid;
  • and hesperidin.

They have calming effects on the nervous system. Valerian also helps:

  • reduce stress levels;
  • improve sleep quality.

This supplement is ideal for those looking to improve their mood and relax.

6. Lavender

Lavender has been famous for centuries as a herbal mood enhancement supplement. It has become a go-to supplement for many due to its many benefits. It has anti-inflammatory properties. They can be beneficial for any aches and pains.

It improves:

  • sleep quality;
  • and can even help with digestive issues like bloating or indigestion.

It’s easy to take. And it can enter your daily routine quickly and conveniently.

7. Ashwagandha

Ashwagandha is an ancient herbal remedy. It helps balance the body and mind. It’s a powerful adaptogen.

This best mood enhancer can:

  • boost cognitive function;
  • and increases serotonin, a neurotransmitter related to happiness.

It is an all-around mood enhancer that can relieve low moods.

8. Magnesium

It can:

  • improve brain function;
  • increase energy levels;
  • and regulate hormones such as dopamine and serotonin.

 They are responsible for controlling moods. Magnesium also helps:

  • nerve and muscle function;
  • reduces inflammation;
  • and promotes a healthy immune system.

9. Zinc

It is an essential mineral that serves as a cofactor for over 300 enzymes. It is involved in many physiological processes. Zinc plays an important role in cognitive functioning and forms the basis for many enzymes. It regulates serotonin production and energy metabolism.

This mood enhancement supplement is effective in treating:

  • anxiety and depression;
  • other mental health issues. 

It can also help boost memory, concentration, and mental clarity. And because zinc is a naturally occurring mineral, it has very few side effects.

10. Creatine

Creatine is a well-known supplement. It has been around since the early 20th century. It’s popular among athletes and bodybuilders. It helps them gain muscle mass quickly.

Creatine helps the brain produce more energy. It allows you to stay focused and motivated.

11. NAC (N-Acetylcysteine)

NAC, or N-Acetylcysteine, is a unique mood enhancement supplement. It doesn’t just attempt to increase serotonin levels in the brain. It helps your body produce:

  • more of its natural serotonin;
  • and other neurotransmitters.

This means that NAC is a longer-lasting and natural solution for mood enhancement.

12. 5-Hydroxytryptophan

5-HTP is a natural feeling booster. It works by increasing the production of serotonin in your brain. It can also help you get better sleep at night, as well as reduce feelings of stress and fatigue during the day. This best mood enhancement supplement can help improve the following:

  • mental clarity;
  • focus, and concentration.

13. Rhodiola

Rhodiola Rosea is an ancient herb with a long history of use throughout Asia and Europe.  It’s known as an adaptogen. Rhodiola has been shown to improve physical performance by increasing endurance levels while helping reduce muscle soreness.   

One interesting fact about Rhodiola Rosea is that it contains a unique compound known as rosavins. It is responsible for many of the plant’s health benefits.

Also, it contains high levels of antioxidants. They can help combat free radicals and protect the body from oxidative damage. It is as effective as some antidepressant medications.

14. Lion’s Mane

It is one of the best mood enhancement supplements around, and here’s why:

  • Lion’s Mane is ancient Chinese medicine. It contains beta-glucans, which are famous for their positive effects on mood regulation;
  • Additionally, it can help support healthy nervous system function;
  • Lion’s Mane is also high in B vitamins and antioxidants. They help to support brain health.

15. Saffron

Saffron is one of the oldest and most prized herbs in the world. It helps with sleep disorders. This best mood supplement can help you fall asleep faster and stay asleep longer.

It also contains many antioxidants that can protect your cells from free radical damage, significantly contributing to aging.

Additionally, saffron helps to boost energy levels. And it makes you feel more alert throughout the day.

How Do Mood Enhancement Supplements Work?

happy mind mood booster

These supplements work in a variety of ways:

  1. They provide vitamins and minerals necessary for healthy brain function. They are B complex vitamins and magnesium. These supplements to improve mood can support energy production and metabolism. Also, they help balance neurotransmitters like serotonin. It helps regulate moods;
  2. These supplements can contain herbs or adaptogens. They are ashwagandha, Rhodiola Rosea, or St. John’s Wort. They have been famous for centuries for their calming effects on the mind and body;
  3. Some of these best mood enhancers can also contain omega-3 fatty acids from fish oil. They can help reduce inflammation and improve focus and overall mental well-being;
  4. Some supplements can also act as natural antidepressants. They help balance hormones, increase serotonin and dopamine levels, and improve sleep.

These supplements should improve your mental and emotional health by improving cognitive functioning.

They allow you to think more clearly and approach life with a positive outlook.

Finally, mood boost requires a holistic approach. So you shouldn’t forget about:

  • healthy eating habits;
  • regular exercise;
  • and adequate rest.

How To Choose The Right Mood-Enhancing Supplement?

Choosing the right mood-enhancing supplement can be tricky. It’s important to remember that not all supplements are created equal. You should look for high-quality ingredients and research their effects on the body:

  • Before committing to a specific supplement, consider your individual needs and health goals. For example, those suffering from chronic stress or anxiety can benefit from calming herbs. And those who need an energy boost can turn to natural stimulants;
  • Research any potential side effects associated with a particular supplement. Certain ingredients such as caffeine can be problematic for some people. They can cause anxiety, insomnia, or restlessness;
  • It is better to take supplements and vitamins in liquid form. They are easier for your body to absorb. For example, the “Happy Mind” liquid mood supplement differs from traditional medicine. They use adaptogens and vitamins to increase overall well-being;
  • Finally, look at the source of the best mood enhancer you are considering. Is it organic? It is important to choose supplements that are high quality and free of contaminants.

All these factors will help ensure you get a safe and effective product that meets your needs.

How To Take Mood Enhancement Supplements Safely And Effectively

There are some essential things you should keep in mind when taking mood enhancement supplements:

  1. Follow the instructions on the product label. Do not exceed the recommended dosage;
  2. Take the supplement to improve mood as prescribed. Do not abruptly stop taking it without consulting a healthcare provider first;
  3. Track Your Progress. Once you start taking a supplement, it’s important to track your progress. So that you can make informed decisions about whether the supplement is working or not, make sure to take note of any changes in energy levels. Consider sleep patterns, moods, or other relevant factors before and after taking the supplement each day;
  4. Take Breaks. If a supplement doesn’t have the desired results, don’t be afraid to take a break from it for a few weeks. And see if that makes a difference. Taking breaks allows your body to adjust better over time. It can help with long-term results.


We hope our list of the top 15 supplements to improve your mood has been helpful. If you’re interested in trying out a mood-enhancing supplement, we suggest starting with one that contains natural ingredients. With careful consideration and guidance, you can find the perfect supplement for your needs and be on your way to a happier, healthier life.


What ingredients do mood supplements include?

Mood supplements typically contain ingredients like B vitamins, amino acids, minerals, and herbs. 

How quickly will I experience the benefits of a mood enhancement supplement?

It depends on your supplement and other factors like your diet and lifestyle. Generally, you can experience an uplifting mood soon after taking the supplement. It can take several days or weeks of consistent use before you feel the full effects. So it’s essential to stick with it and be patient.

Are there any foods or beverages to avoid while taking a mood enhancement supplement?

You should avoid such beverages as caffeine and alcohol. It’s best to supplement with meals containing whole foods, such as fresh fruits and vegetables, lean proteins and whole grains. Finally, be sure to drink plenty of water and get enough rest. It is vital for maintaining good mental health.

Is it safe to take multiple mood enhancement supplements simultaneously?

No, it is not advisable to take multiple mood enhancement supplements simultaneously. It can increase the risk of experiencing negative side effects. And it can even interfere with each other’s efficacy. 

What to take for mood swings?

You should take Vitamin complex based on B vitamins. If you have sleep deprivation and stress, vitamin B (especially B6) can neutralize hysterical states, relieves anxiety and depression,
and improves thought processes. It also has a beneficial effect on blood pressure, the fluctuations that often accompany stress.

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